University of Illinois Chicago · PharmacologyFreitag Invasion Lab
Nancy Elizabeth Freitag · Chicago, Illinois
Research Focus
Dr. Nancy Elizabeth Freitag's lab studies the bacteria Listeria monocytogenes, which can cause serious infections, especially in pregnant women. The research focuses on understanding how certain strains of this bacterium invade the placenta and affect fetal development. By uncovering the mechanisms behind this infection, the lab aims to improve infection management and maternal-fetal health outcomes.
Listeria monocytogenesplacental invasionfetal developmentmaternal-fetal transmissionimmune signaling
Research Aims
3AIM 01Define the mechanisms of InlB surface localization and activity.
AIM 02Investigate the impact of InlB on Listeria's vertical transmission.
AIM 03Explore maternal and fetal immune responses to Listeria infection.
Skills the Lab Values
cell culturemouse modelsimmunohistochemistryWestern blotPCRin vivo imagingbacterial samplingflow cytometrydata analysisbioinformatics
Output against the department
Publications122bottom 35% of dept.301st of 462
this lab
most publishedleast published
Citations5.1kbottom 37% of dept.289th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.