Columbia University in the City of New York · BiologyAngiopoietin Signaling and Metastasis Lab
Minah Kim · New York, New York
Research Focus
Dr. Minah Kim's lab focuses on understanding how the Angiopoietin-2/Tie2 signaling pathway affects liver metastasis in pancreatic neuroendocrine tumors (PanNET). By investigating the mechanisms of tumor growth and immune evasion, the lab aims to improve treatment strategies for patients suffering from this aggressive cancer. Ultimately, the research seeks to identify potential biomarkers that could help guide clinical decisions for better management of metastatic disease.
Angiopoietin-2Tie2 signalingpancreatic neuroendocrine tumorsliver metastasisimmune evasionimmune checkpoint inhibitorsvascular destabilizationbiomarkerstumor progression
Research Aims
3AIM 01Investigate the role of Ang2-mediated vascular destabilization in liver metastasis of PanNET.
AIM 02Evaluate how Ang2 inhibition impacts immune cell infiltration in liver metastases.
AIM 03Identify circulating sTie1 levels as a prognostic biomarker for PanNET patients.
Skills the Lab Values
cell culturemouse modelsflow cytometryimmunohistochemistryWestern blotbiostatisticsfunctional assaysgenetic manipulationbiomarker analysis
Output against the department
Publications342top 15% of dept.151st of 1,033
this lab
most publishedleast published
Citations4.7kbottom 36% of dept.658th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.