University of North Carolina at Chapel Hill · PharmacologyAinslie Immunotherapy Lab
Kristy M Ainslie · Chapel Hill, North Carolina
Research Focus
Dr. Kristy M. Ainslie's lab focuses on innovative therapies for challenging medical conditions such as glioblastoma and autoimmune diseases. By using biomaterials, particularly specialized biodegradable polymers, the lab aims to improve the effectiveness of immune cell therapies and develop new strategies for inducing immune tolerance. The research integrates advanced materials with cell therapy to enhance patient outcomes and advance the field of immunotherapy.
GlioblastomaCAR-T therapyNKT cell therapybiomaterialsimmune tolerancemicroparticlesmultiple sclerosisIL-10biodegradable polymersimmunotherapy
Research Aims
3AIM 01Enhance CAR-T/NKT cell therapy efficacy using innovatively designed biomaterials.
AIM 02Investigate the interaction between biodegradable microparticles and B cells to promote IL-10 production.
AIM 03Optimize therapeutic protocols for antigen specific tolerance in autoimmune diseases.
Skills the Lab Values
biomaterial synthesiscell cultureanimal modelsmicroparticle characterizationflow cytometryRNA sequencingin vivo experimentsimmune cell engineeringpharmacologic studiesdata analysis
Output against the department
Publications179bottom 49% of dept.237th of 462
this lab
most publishedleast published
Citations5.0kbottom 37% of dept.291st of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.