University of Chicago · GeneticsOber Lab
Carole Ober · Chicago, Illinois
Research Focus
Dr. Carole Ober's lab at the University of Chicago focuses on understanding asthma and allergic diseases, which affect many people around the world. The lab aims to identify genetic factors that contribute to these diseases and to explore how they impact different types of immune cells in the body. By doing this research, they hope to uncover new drug targets that can lead to better treatments for patients.
asthmaallergic diseasesgenomicsdrug targetsimmunologyGWASprecision medicinecell typesgenetic variantsbiobank
Research Aims
5AIM 01Identify genetic variants associated with asthma and allergic diseases.
AIM 02Characterize the functional effects of these variants in relevant cell types.
AIM 03Explore the immunologic effects of variants on lung immune cells.
AIM 04Analyze data from diverse asthma cohorts and the UK Biobank.
AIM 05Develop novel drug targets for precision medicine in asthma.
Skills the Lab Values
genome-wide association studies (GWAS)cell cultureanimal models (mouse)immunologic assaysRNA sequencingDNA manipulationstatistical analysisbioinformaticsphenotypingflow cytometry
Output against the department
Publications600top 9% of dept.24th of 259
this lab
most publishedleast published
Citations39ktop 16% of dept.41st of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.