University of Utah · BiologyHaecker Immunology Lab
Hans Haecker · Salt Lake City, Utah
Research Focus
Dr. Hans Haecker's lab focuses on understanding how specific proteins and signaling pathways contribute to inflammatory diseases, particularly systemic lupus erythematosus (SLE). By investigating the roles of proteins in the Toll-like receptor (TLR) signaling pathway, the lab aims to uncover the mechanisms that lead to inappropriate immune responses. This research not only enhances our understanding of SLE but may also identify potential targets for new therapies.
Toll-like Receptorsinflammationsystemic lupus erythematosusprotein interactionsimmune response
Research Aims
3AIM 01Investigate the signaling mechanisms of TLRs in inflammation.
AIM 02Characterize the role of LYN and IRF5 in lupus pathology.
AIM 03Identify the E3 ubiquitin ligase involved in the TLR pathway.
Skills the Lab Values
mouse modelsbiochemical assaysCRISPR/Cas technologyquantitative mass spectrometrygene expression analysis
Output against the department
Publications12bottom 2% of dept.1,016th of 1,033
this lab
most publishedleast published
Citations275bottom 1% of dept.1,021st of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.