Yale University · BiochemistryRibosome Biogenesis Research Lab
Susan J Baserga · New Haven, Connecticut
Research Focus
Dr. Susan Baserga's lab at Yale University focuses on understanding the process of ribosome biogenesis and its links to human genetic diseases. They utilize innovative approaches, including genome-wide screening techniques, to identify proteins and non-coding RNAs that regulate ribosome production. By investigating how these processes affect cellular function in various tissues and during development, the lab aims to uncover the foundations of ribosomopathies, which are disorders tied to abnormal ribosome function.
ribosome biogenesisribosomopathiesgenetic diseasesmicroRNAscellular assays
Research Aims
5AIM 01Identify new proteins involved in ribosome biogenesis
AIM 02Characterize the role of non-coding RNAs in ribosome production
AIM 03Investigate how ribosome biogenesis regulates human diseases
AIM 04Explore regulatory pathways involved in ribosomal function
AIM 05Utilize model organisms to study ribosome function in development
Skills the Lab Values
RNA interference (RNAi)genome-wide siRNA screeningcell cultureimaging techniquesdata analysis with Python
Output against the department
Publications142bottom 40% of dept.240th of 402
this lab
most publishedleast published
Citations7.5kbottom 41% of dept.239th of 402
this lab
most citedleast cited
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