UWMUniversity of Wisconsin-Madison · Genetics
The Midbody Connection Lab
Ahna Renee Skop · Madison, Wisconsin
Research Focus
Ahna Renee Skop's lab at the University of Wisconsin-Madison investigates how midbody remnants (MBRs), a special type of extracellular vesicle that cells release during division, help with communication between cells. This research explores the molecular contents of MBRs and their roles in health issues like cancer and neurodevelopmental disorders such as autism. The lab uses a range of techniques to delve into how these vesicles can carry information, potentially influencing new treatments for diseases.
midbody remnantsextracellular vesiclescell-cell communicationcancerneurodevelopmental disordersRNA transfervirusescell divisiontherapeutic targets
Research Aims
4AIM 01Investigate the molecular cargo of midbody remnants in different cell types.
AIM 02Elucidate how recipient cells recognize and internalize midbody remnants.
AIM 03Examine how viruses may use the midbody remnants pathway for transmission.
AIM 04Profile midbody remnant content changes during neural progenitor cell differentiation.
Skills the Lab Values
RNA extractioncell culturelive-cell imagingtranscriptomicsproteomicsbiochemical assaysfunctional perturbation studiesviral RNA localizationcell differentiation studies
Output against the department
Publications48bottom 8% of dept.237th of 259
this lab
most publishedleast published
Citations1.9kbottom 7% of dept.241st of 259
this lab
most citedleast cited
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