Stanford University · Microbiology & ImmunologyViral Circular RNA Research Group
Peter Sarnow · Stanford, California
Research Focus
Dr. Peter Sarnow's lab at Stanford University focuses on understanding how certain viruses use circular RNAs to impact infection outcomes. They investigate how these virus-derived circular RNAs, produced during infections by viruses like hepatitis C and SARS-CoV-2, might influence viral behavior and potentially lead to new antiviral strategies. This research is crucial for developing effective treatments and vaccines against viral diseases, particularly in the context of emerging viral variants and diseases.
circular RNAsviral infectionshepatitis CSARS-CoV-2enterovirus 71antiviral developmentRNA biologygene expressionviral proteinsvaccine research
Research Aims
5AIM 01Investigate the functional roles of virus-derived circular RNAs in modulating viral gene expression.
AIM 02Examine the mechanistic insights into vcircRNA actions through localization and protein interactions.
AIM 03Determine the contributions of RNA ligases to the synthesis of virus-derived circular RNAs.
AIM 04Explore the implications of vcircRNAs for viral pathogenesis and potential therapeutic targets.
AIM 05Assess the broader significance of circular RNAs across different RNA virus families.
Skills the Lab Values
cell culturebiochemical assaysbioinformaticsCRISPR/Cas13 gene editingRNA extractionWestern blottingmicroscopygenetic engineeringviral propagationprotein purification
Output against the department
Publications190top 34% of dept.166th of 486
this lab
most publishedleast published
Citations22ktop 17% of dept.82nd of 486
this lab
most citedleast cited
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