Boston University · BiochemistryGarcia-Marcos Lab
Mikel Garcia-Marcos · Boston, Massachusetts
Research Focus
Dr. Mikel Garcia-Marcos leads a research lab at Boston University Medical Campus that focuses on understanding how G proteins, which are important for cellular signaling, operate and can be regulated. His team investigates novel regulatory components that influence G protein pathways, particularly in relation to neurological diseases like Alzheimer's. The lab employs innovative techniques to explore the flexibility and complexity of these signaling mechanisms, aiming to find new ways to treat cognitive decline and related disorders.
G proteinsneurological disorderssignaling mechanismsAlzheimer's Diseasecellular communicationneuroscienceinnovative technologies
Research Aims
3AIM 01Define the physiological role of GINIP in cognitive function and aging.
AIM 02Investigate molecular mechanisms that regulate GINIP's G protein signaling.
AIM 03Identify and characterize new G protein regulators similar to GINIP.
Skills the Lab Values
cell cultureimmunofluorescencegenetic engineeringmolecular cloningbiochemical assaysoptical biosensingtransgenic mouse modelsdata analysisprotein purificationsignal transduction pathways
Output against the department
Publications153bottom 43% of dept.229th of 402
this lab
most publishedleast published
Citations7.2kbottom 38% of dept.248th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.