Johns Hopkins University · NeuroscienceMueller Lab
Ulrich Mueller · Baltimore, Maryland
Research Focus
Dr. Ulrich Mueller's laboratory at Johns Hopkins University focuses on understanding the function of hair cells in the inner ear, which are critical for hearing. The lab studies specific genes linked to hearing loss and how those genes affect the development and function of these hair cells. Researchers investigate the mechanisms of signal transmission in auditory circuits and the impact of genetic mutations on hearing capability.
hair cellshearing lossmechanotransductionauditory neuronsgenetic modeling
Research Aims
5AIM 01Investigate the role of CLRN1 and CLRN2 in hair cell development and function.
AIM 02Examine how mechanical forces affect the mechanotransduction complex in hair cells.
AIM 03Study the connectivity and functioning of spiral ganglion neurons in relation to hair cell signaling.
AIM 04Identify genetic factors that cause defects in hair cell function linked to hearing loss.
AIM 05Explore the molecular mechanisms behind hearing impairment due to genetic mutations.
Skills the Lab Values
PCRimmunohistochemistryelectrophysiologymouse modelsbiochemical assayscell culturegenomic techniquesscanning electron microscopydata analysis
Output against the department
Publications125bottom 44% of dept.375th of 671
this lab
most publishedleast published
Citations142ktop 1% of dept.8th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.