University of Virginia-Main Campus · BiologyParichy Pigmentation Lab
David M Parichy · Charlottesville, Virginia
Research Focus
Dr. David Parichy's lab at the University of Virginia studies how adult traits originate and are maintained, particularly through the development of pigment cells in zebrafish. By examining the genetic and cellular mechanisms of these processes, the lab aims to understand how variations in cell types contribute to different patterns and structures. This research has implications for understanding human genetic diseases, developmental biology, and regenerative medicine.
zebrafishpigmentationneural crestdevelopmental biologymorphogenesisstem cellspattern formationgeneticsregenerative medicinepublic health
Research Aims
5AIM 01Investigate how pigment cell progenitors are specified during development.
AIM 02Elucidate the cellular interactions necessary for pigment pattern formation.
AIM 03Analyze how positional information affects pigment cell location.
AIM 04Study evolutionary changes in cell type diversification in zebrafish and related species.
AIM 05Explore the implications of developmental mechanisms for regenerative medicine.
Skills the Lab Values
zebrafish husbandrygenetic manipulationbehavioral assayshigh-resolution imagingcell culturemutation analysiscomparative biologydata analysisgenomicsmolecular biology
Output against the department
Publications146top 47% of dept.483rd of 1,033
this lab
most publishedleast published
Citations10ktop 37% of dept.383rd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.