University of North Carolina at Chapel Hill · GeneticsThe Immune Nexus Lab
Jenny P Ting · Chapel Hill, North Carolina
Research Focus
Dr. Jenny Ting's lab focuses on understanding how innate immune receptors, which play a critical role in the body's defense against infections and cancer, function and interact with various biological processes. The lab investigates how these receptors recognize DNA, their unexpected roles in adaptive immune cells like T and B lymphocytes, and their implications in diseases such as colorectal cancer and COVID-19. By exploring these aspects, the research aims to enhance immunotherapy strategies and improve our understanding of immune responses during infections.
innate immunitycancer immunotherapyinflammasomesCOVID-19DNA recognitionadaptive immunitycolorectal cancercytokine stormmicrobiomeimmune receptors
Research Aims
5AIM 01Identify the structure of DNA recognized by innate immune receptors.
AIM 02Investigate the roles of AIM2 and STING in T and B lymphocytes.
AIM 03Examine the impact of innate immune receptors on colorectal cancer progression.
AIM 04Explore the complex interactions between inflammation, microbiome, and cancer.
AIM 05Understand the mechanisms behind cytokine release during COVID-19.
Skills the Lab Values
PCRcell cultureflow cytometryWestern blotRNA sequencingmicroscopyprotein purificationanimal modelsbiochemical assaysgenetic manipulation
Output against the department
Publications388top 19% of dept.49th of 259
this lab
most publishedleast published
Citations32ktop 18% of dept.47th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.