University of Colorado Denver/Anschutz Medical Campus · Mathematics & Statistics

Pathway Innovations Lab

Yue Wang · Denver, Colorado

Research Focus

Dr. Yue Wang's research lab at the University of Colorado Denver focuses on improving the analysis of gene pathways to better understand complex human diseases. They are developing advanced statistical models that can accurately capture the interactions between genes and their effects on health, particularly using data from RNA sequencing. Their innovative approaches aim to reduce inaccuracies in current pathway analysis methods, paving the way for groundbreaking insights into disease mechanisms.

RNA-seqgene pathway analysisstatistical modelinglatent factor modelspublic healthbioinformaticsphenotype associationsindividual gene expressionpathway interactions

Research Aims

AIM 01Develop advanced models for unsupervised pathway interaction analysis.

AIM 02Identify pathway-phenotype associations using multivariable regression.

AIM 03Reduce false discoveries in pathway analysis methods.

AIM 04Validate results using extensive RNA-seq datasets.

AIM 05Unlock insights into genetic regulation of complex diseases.

Skills the Lab Values

RNA sequencingmultivariable regression modelingstatistical analysisdata visualizationbioinformatics toolscomputational biologylatent variable modelingdata interpretationresearch methodology

Pathway Innovations Lab

Research Focus

Research Aims

Skills the Lab Values

Output against the department