Duke University · Biomedical EngineeringSkeletal Muscle Regeneration Lab
Nenad Bursac · Durham, North Carolina
Research Focus
Dr. Nenad Bursac's lab focuses on developing advanced engineered human skeletal muscle tissues to better understand and study muscle regeneration and the role of muscle stem cells. By creating complex 3D tissue models that mimic the natural environment of muscle stem cells, the lab aims to explore how different cell types interact and how these interactions affect muscle health and recovery. This research has significant implications for treating diseases like muscular dystrophies and improving muscle repair mechanisms.
skeletal musclemuscle regenerationstem cellstissue engineeringbiomimetics
Research Aims
4AIM 01Develop engineered human skeletal muscle tissues to study muscle stem cell niches.
AIM 02Investigate the complex interactions between muscle cells, blood vessels, and neurons.
AIM 03Enhance the regenerative response of engineered muscle tissues for better modeling of muscle disorders.
AIM 04Create a biomimetic culture model for studying human muscle physiology and disease.
Skills the Lab Values
3D cell culturecell differentiationmuscle tissue engineeringco-culture techniquesextracellular matrix analysis
Output against the department
Publications214top 50% of dept.295th of 595
this lab
most publishedleast published
Citations12ktop 30% of dept.176th of 595
this lab
most citedleast cited
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