University of Florida · PharmacologyNeurodegeneration Protein Interaction Lab
May Khanna · Gainesville, Florida
Research Focus
Dr. May Khanna's research lab at the University of Florida focuses on understanding the interactions between TDP-43 and Tau proteins, which are important in Alzheimer's disease and other neurodegenerative disorders. The lab studies how these proteins interact under normal and pathological conditions, and explores potential therapeutic interventions to disrupt harmful interactions. This research could lead to innovative treatments for neurodegenerative diseases.
TDP-43TauneurodegenerationAlzheimer's Diseaseprotein interaction
Research Aims
5AIM 01Investigate the interaction between TDP-43 and Tau proteins.
AIM 02Characterize the binding dynamics using biophysical techniques.
AIM 03Examine the physiological and pathological effects of their interaction.
AIM 04Test small molecules for disrupting their interaction.
AIM 05Identify novel therapeutic targets for Alzheimer's disease and related disorders.
Skills the Lab Values
NMR spectroscopysurface plasmon resonancecell culturehumanized disease modelsimmunoprecipitationmolecular biology techniquesbiophysical assaysin vivo analysisdrug testing techniques
Output against the department
Publications90bottom 21% of dept.362nd of 462
this lab
most publishedleast published
Citations3.1kbottom 23% of dept.355th of 462
this lab
most citedleast cited
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