University of Vermont · BiochemistryStein Epigenetics Lab
Gary S. Stein · Burlington, Vermont
Research Focus
Dr. Gary S. Stein's lab focuses on understanding how genome organization and epigenetic control influence gene expression, particularly in breast cancer. By exploring the interactions between epigenetic modifications and nuclear organization, the team aims to uncover mechanisms that could lead to new diagnostic and therapeutic approaches in cancer treatment. The lab employs advanced techniques to study both normal and cancerous breast cell behaviors and their response to various treatments.
epigeneticsbreast cancergenome organizationgene expressiontranscription factors
Research Aims
3AIM 01Investigate the role of mitotic gene bookmarking in breast cancer.
AIM 02Examine the function of bromodomain chromatin readers in endocrine therapy resistance.
AIM 03Profile long noncoding RNAs in aggressive breast cancer to understand their impact on genome organization.
Skills the Lab Values
cell culturemouse modelsRNA sequencingbioinformaticschromatin immunoprecipitation (ChIP)super-resolution microscopydrug response assays
Output against the department
Publications660top 5% of dept.21st of 402
this lab
most publishedleast published
Citations31ktop 11% of dept.45th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.