University of Illinois Chicago · ChemistryZhou Lab
Huan-Xiang Zhou · Chicago, Illinois
Research Focus
Dr. Huan-Xiang Zhou's lab at the University of Illinois at Chicago focuses on studying the interactions between biomolecules, particularly how certain proteins and DNA interact and behave. This research aims to uncover fundamental principles of molecular recognition, which is crucial in many biological processes, and has potential applications in drug design and therapy development. The lab combines experimental and computational techniques to gain insights into biomolecular properties and behaviors inside cells.
biomolecular recognitionintrinsically disordered proteinsbiomolecular condensatesprotein-DNA interactionsdrug delivery
Research Aims
3AIM 01Investigate the binding mechanisms of intrinsically disordered proteins with small molecules, membranes, and DNA.
AIM 02Characterize the physical properties of biomolecular condensates and the effects of specific amino acids.
AIM 03Conduct in-cell studies to explore the roles of biomolecular condensates in cellular functions and drug delivery.
Skills the Lab Values
molecular dynamics simulationsprotein purificationfluorescence microscopysingle-molecule force spectroscopycell culturebioinformaticsspectroscopyNMR spectroscopybiophysical characterization
Output against the department
Publications607top 13% of dept.28th of 216
this lab
most publishedleast published
Citations23ktop 20% of dept.44th of 216
this lab
most citedleast cited
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