Binghamton University · EngineeringPulmonary Nodule Diagnostics Unit
Yuan Wan · Vestal, New York
Research Focus
Dr. Yuan Wan's research lab at Binghamton University focuses on developing a quick and efficient method for diagnosing solitary pulmonary nodules (SPNs), which can be either benign or malignant. By utilizing liquid biopsies that examine extracellular vesicles (small particles released by cells), the lab aims to create a diagnostic tool that can provide results within five days, significantly improving patient care compared to current imaging methods. Their goal is to enhance the understanding of lung cancer genetics and aid in timely treatment decisions.
liquid biopsyextracellular vesiclessolitary pulmonary nodulelung cancermolecular diagnosticsgene mutation panel
Research Aims
3AIM 01Develop a microdevice for isolation of extracellular vesicles from plasma.
AIM 02Customize a gene mutation panel for lung adenocarcinoma.
AIM 03Analyze mutation concordance between tissue DNA and plasma EV DNA.
Skills the Lab Values
DNA extractiongene sequencingmicrodevice fabricationplasma processingmutation analysiscell culturePCRnext-generation sequencingdata analysis
Output against the department
Publications136bottom 32% of dept.189th of 278
this lab
most publishedleast published
Citations4.9kbottom 37% of dept.174th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.