Yale University · GeneticsLu GlycoRNA Lab
Jun Lu · New Haven, Connecticut
Research Focus
Jun Lu's research lab at Yale focuses on understanding the role of cell surface RNAs, specifically in neutrophils — critical immune cells that respond to inflammation. The lab investigates glycosylated RNAs, known as glycoRNAs, which are found on the surface of these cells and may influence how neutrophils interact with blood vessels and tissues. This research has the potential to reveal new mechanisms of immune response regulation and contribute to our knowledge of human diseases related to inflammation.
glycoRNAsneutrophilscell surface RNAsimmune responseinflammation
Research Aims
4AIM 01Investigate the presence of glycoRNAs on neutrophil cell surfaces.
AIM 02Determine the functional roles of cell surface RNAs in neutrophil behavior.
AIM 03Explore the interaction mechanisms between neutrophils and endothelial cells.
AIM 04Advance understanding of the chemical nature of glycoRNAs in neutrophils.
Skills the Lab Values
cell culturein vitro assaysflow cytometryRNA extractionmicroscopymolecular cloninggel electrophoresismass spectrometryanimal modelsintravital imaging
Output against the department
Publications1,123top 3% of dept.9th of 259
this lab
most publishedleast published
Citations101ktop 5% of dept.13th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.