Columbia University in the City of New York · NeuroscienceCenter for Pediatric Neurogenetics
Tristan T Sands · New York, New York
Research Focus
Dr. Tristan T. Sands' lab at Columbia University focuses on understanding and treating complex neurological disorders in children, specifically Developmental and Epileptic Encephalopathies (DEE). The lab studies the genetic aspects of these disorders and utilizes genetically engineered mice to explore new gene therapy techniques. By investigating when and how gene changes affect neuron development, the lab aims to create effective therapies that can help manage DEE symptoms for affected families.
epilepsygene therapyneurodevelopmental disordersmouse modelsepileptic encephalopathies
Research Aims
4AIM 01Investigate the genetic factors contributing to Developmental and Epileptic Encephalopathies.
AIM 02Examine the timing and delivery methods of gene therapy in mouse models.
AIM 03Evaluate the impact of genetic manipulation on neuron development and DEE progression.
AIM 04Test the efficacy of RNA-based gene therapies for mitigating DEE symptoms.
Skills the Lab Values
geneticsmouse modelsgene expression analysisRNA-based therapyelectrophysiology
Output against the department
Publications68bottom 18% of dept.547th of 671
this lab
most publishedleast published
Citations1.4kbottom 9% of dept.613th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.