University of Pennsylvania · BiologyThe Genetic Echo Lab
Wan-Ping Lee · Philadelphia, Pennsylvania
Research Focus
Dr. Wan-Ping Lee's lab at the University of Pennsylvania focuses on understanding Alzheimer's Disease (AD), a major public health concern. The research emphasizes the role of genetic factors, particularly copy number variations (CNVs), in the disease's etiology and progression. By analyzing whole genome sequencing data from a large and diverse population, the lab aims to identify new genetic risk factors and improve strategies for the treatment and prevention of AD.
Alzheimer's Diseasegeneticscopy number variationsgenome sequencingethnic diversity
Research Aims
3AIM 01Detect and genotype copy number variations in AD patients and controls.
AIM 02Identify genome regions associated with Alzheimer's disease risk.
AIM 03Explore ethnic-specific and shared genetic risk factors for Alzheimer's disease.
Skills the Lab Values
whole genome sequencinggenotype callingassociation analysisbioinformaticsdata analysiscomputational pipelinesDockerBioconductorstatistical geneticspopulation genetics
Output against the department
Publications7bottom 1% of dept.1,024th of 1,033
this lab
most publishedleast published
Citations40ktop 7% of dept.74th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.