RUThe Rockefeller University · Biology
Tavazoie Lab
Sohail F. Tavazoie · New York, New York
Research Focus
Dr. Sohail F. Tavazoie's lab at Rockefeller University focuses on understanding the biology and genetics behind the process of metastasis, which is how cancer spreads from its original site to other parts of the body. By examining how certain genetic variants and microRNAs influence metastasis, the lab aims to identify critical pathways that could lead to new therapies for cancer. Their work has significant implications for developing targeted treatments that can prevent or reduce metastasis in various cancers.
metastasisgenetic variantsmicroRNAsApoEcancer therapymelanomabreast cancercolorectal cancer
Research Aims
5AIM 01Investigate the role of genetic variants in cancer metastasis.
AIM 02Identify microRNAs that influence metastasis formation.
AIM 03Explore the mechanisms of ApoE signaling in cancer progression.
AIM 04Develop novel therapeutic approaches targeting metastasis.
AIM 05Extend hereditary cancer genetics to other types of cancers.
Skills the Lab Values
mouse modelsgenetic screeningoptical imagingcell cultureWestern blotPCRclinical trial designdata analysistransgene expressionbioinformatics
Output against the department
Publications121bottom 43% of dept.586th of 1,033
this lab
most publishedleast published
Citations12ktop 29% of dept.304th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.