University of Connecticut · GeneticsGenomic Harmony Lab
Christine R Beck · Storrs, Connecticut
Research Focus
Dr. Christine R. Beck's lab at the University of Connecticut focuses on understanding how repetitive sequences in mammalian genomes contribute to genetic variation and stability. Through the study of transposable elements and structural rearrangements, the lab explores their effects on gene regulation and the mechanisms that protect the genome from instability. This research is particularly relevant for uncovering the genetic basis of diseases such as cancer, stemming from genomic instability.
genome variationtransposable elementsgenomic instabilitygene regulationmammalian evolutionepigeneticsstructural variants
Research Aims
5AIM 01Investigate the role of repetitive sequences in driving genome variation in mammals.
AIM 02Identify mechanisms that guard against genomic instability caused by transposable elements.
AIM 03Explore how repeat variation affects gene regulation across evolution.
AIM 04Characterize the impact of structural variants on human health.
AIM 05Employ computational tools to analyze large genomic datasets.
Skills the Lab Values
molecular genomicscomputational biologyDNA sequencingbioinformaticsepigenetic analysisgenetic mappingcell culturedata visualizationtranscriptomics
Output against the department
Publications96bottom 30% of dept.182nd of 259
this lab
most publishedleast published
Citations6.5kbottom 35% of dept.168th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.