Johns Hopkins University · Microbiology & ImmunologyB Cell Immunology Lab
Nicole Baumgarth · Baltimore, Maryland
Research Focus
The Baumgarth lab at Johns Hopkins University focuses on understanding how B cells respond during influenza infections to improve vaccine design. They investigate how innate immune signals regulate B cell activation and help generate strong antibody responses. By studying the mechanisms behind B cell differentiation and memory, the lab aims to find ways to create vaccines that offer longer-lasting protection against viruses like influenza.
B cellsinfluenzaadaptive immunityvaccine designhumoral immunity
Research Aims
3AIM 01Investigate how TLR3 and MyD88 signals support B cell differentiation during influenza infection.
AIM 02Determine the role of distinct B cell populations in extrafollicular responses.
AIM 03Analyze how early B cell activation influences antibody quality post-infection.
Skills the Lab Values
cell cultureflow cytometryimmunization techniquesmouse modelsantibody assays
Output against the department
Publications187top 35% of dept.172nd of 486
this lab
most publishedleast published
Citations12ktop 29% of dept.143rd of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.