University of Florida · GeneticsBoulant Hypoxia Lab
Steeve Boulant · Gainesville, Florida
Research Focus
Dr. Steeve Boulant's lab focuses on understanding how low oxygen levels in the gut affect the body's ability to fight off viral infections, particularly enteric viruses that can cause severe gastrointestinal diseases. By studying human intestinal epithelial cells and using innovative technologies like organ-on-a-chip, the lab investigates how different types of intestinal cells respond to these conditions and how this knowledge can lead to new treatments for infections and inflammatory bowel diseases.
hypoxiaimmune responseenteric virusesintestinal epithelial cellsorganoids
Research Aims
4AIM 01Investigate how hypoxia impacts the immune response of intestinal epithelial cells during viral infections.
AIM 02Characterize distinct microenvironments in the gut and their roles in virus susceptibility.
AIM 03Determine the specific responses of stem cells and differentiated cells to low oxygen levels.
AIM 04Develop strategies to manipulate immune responses to combat enteric viruses and inflammatory bowel diseases.
Skills the Lab Values
cell cultureRNA sequencinghypoxia assaysmicroscopyorgan-on-a-chip technology
Output against the department
Publications163top 48% of dept.125th of 259
this lab
most publishedleast published
Citations11ktop 46% of dept.119th of 259
this lab
most citedleast cited
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