Ohio State University-Main Campus · NeuroscienceThe Chromatin Regeneration Lab
Ilaria Palmisano · Columbus, Ohio
Research Focus
Dr. Ilaria Palmisano's lab at Ohio State University focuses on understanding how the structure of DNA, specifically its 3D organization, affects the ability of nerves to regenerate after injuries. This research is crucial because nerve injuries can lead to long-lasting health issues and disabilities. By manipulating the molecular mechanisms involved in gene expression, the lab aims to develop new therapeutic strategies to enhance nerve repair and recovery.
nerve regenerationchromatin architecturegene expressionperipheral nerve injurytranscriptional reprogrammingsuper-resolution imagingfunctional genomicsaxonal growthepigenetic mechanismsmolecular modulation
Research Aims
3AIM 01Investigate the molecular mechanisms by which enhancer-promoter interactions promote regenerative gene transcription after nerve injury.
AIM 02Identify regulators of the transcription machinery at chromatin contacts and their roles in axon growth.
AIM 03Characterize known regulators of 3D chromatin architecture and explore their potential to enhance nerve regeneration.
Skills the Lab Values
high-throughput transcriptomicsgenome-wide mappingmouse modelssuper-resolution imagingbiochemical assaysfunctional genomicsRNA sequencingchromatin immunoprecipitationcell culturebiological assays
Output against the department
Publications44bottom 9% of dept.612th of 671
this lab
most publishedleast published
Citations1.5kbottom 9% of dept.610th of 671
this lab
most citedleast cited
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