Dr. Adriano Marchese's lab focuses on understanding how GPCR signaling works, particularly looking at a receptor involved in various diseases, including cancer. They aim to uncover the mechanisms behind this signaling to help develop new therapeutic strategies. The lab uses a variety of advanced techniques to study these complex interactions in cell models.

Dr. Brian Volkman’s lab at the Medical College of Wisconsin focuses on understanding the protein interactions and signaling mechanisms involved in chronic pancreatitis and the evolution of metamorphic proteins. His team investigates how specific chemokines like CCL28 influence inflammation in the pancreas, potentially leading to cancer, and develops new proteins that can switch their structure to perform different functions. The ultimate goal is to identify novel therapies that could mitigate chronic inflammation and improve treatments for pancreatic diseases.