Richard W. Carthew's lab at Northwestern University studies gene regulation in developmental biology, primarily using the fruit fly Drosophila as a model organism. The research focuses on understanding the roles of non-coding RNAs, particularly long non-coding RNAs, in gene regulation and cell fate during development. Additionally, the lab investigates how external signals and tissue morphology influence cellular processes and development, utilizing advanced mathematical models and experimental techniques.

Dr. Issam Ben-Sahra's lab at Northwestern University focuses on understanding how cells grow and develop by studying the complex interactions between nutrient signaling and nucleotide metabolism. They investigate the molecular mechanisms that link signaling pathways to nucleotide production, which are critical for various cell functions like growth and energy production. Their recent work has reshaped our understanding of how nucleotides influence cellular metabolism and has implications for developing new therapeutic strategies.

Dr. Ali Shilatifard's lab focuses on understanding how mutations in chromatin modifiers like MLL4 contribute to cancer, especially bladder cancer. His research combines biochemical studies with pre-clinical trials to explore how these mutations can inform targeted therapies and improve patient treatment options. By studying specific mutations and their effects, the lab aims to develop biomarkers for better cancer diagnostics and treatment strategies.