Professor Matthew David Macmanes at the University of New Hampshire studies why some rodents can survive with very little water. His lab focuses on understanding the biological and genetic factors that allow these animals to tolerate dehydration. The goal of the research is to apply this knowledge to improve human health, particularly for vulnerable populations who suffer from dehydration. By learning how these rodents manage water loss and preserve organ function, the lab aims to find new ways to help humans cope with dehydration-related health risks.

Dr. Sherine F. Elsawa's lab focuses on understanding how a specific protein called GLI2 helps control the production of antibodies by B cells, which are essential for our immune response. The lab uses both special human B cell lines and genetically modified mice to explore how GLI2 affects the transcription of immunoglobulin genes, which are vital in responding to infections and diseases. This research is particularly important for understanding immune disorders where antibody production goes awry, like certain autoimmune diseases and cancers.