Hannele Ruohola-Baker · Biochemistry
Dr. Hannele Ruohola-Baker's lab at the University of Washington focuses on understanding the genetic factors involved in craniofacial disorders, such as cleft lip and palate, to develop targeted therapies. They use advanced techniques like spatial transcriptomics to study human tissues and induced pluripotent stem cells to model these disorders. This research aims to reveal the complex networks that control the development of the face and improve treatment options for common birth defects.
Justin M Kollman · Biochemistry
Dr. Justin Kollman's lab at the University of Washington focuses on the structure and function of metabolic enzyme assemblies. They study how different enzymes in cells organize and work together to maintain metabolic balance, especially under changing environmental conditions. By understanding these assemblies, the lab aims to uncover insights into diseases linked to metabolic dysfunction and the potential for new medical therapies.
Rachel E Klevit · Biochemistry
Professor Rachel Klevit's lab at the University of Washington studies how proteins are modified by a process called ubiquitylation, which affects their function and stability in cells. This research is important for understanding various human diseases, including cancer, as the modification of proteins can influence cellular processes such as growth and stress responses. The lab focuses on the proteins involved in this modification process and aims to uncover new therapeutic targets to address these diseases.