David Eliezer's research lab at Weill Medical College focuses on the intriguing role of intrinsically disordered proteins (IDPs) in cell biology, particularly in how they interact with cellular membranes and contribute to important processes such as membrane trafficking and organization. The lab seeks to understand how these dynamic proteins achieve their functions despite lacking a stable structure, with implications in areas like neuron signaling and the formation of membraneless organelles. By studying specific protein models, the lab aims to shed light on the mechanisms that govern cellular organization and communication.

Dr. Timothy McGraw's lab focuses on understanding how incretin hormones, specifically GIP and GLP-1, control metabolism in the body. These hormones are important for regulating insulin secretion and sensitivity, with potential applications in treating diabetes, heart disease, and even neurodegenerative disorders. The lab develops mouse models to explore the molecular mechanisms of GIP receptor signaling, which could lead to improved therapies targeting these hormones.

Dr. Joshua Levitz's lab focuses on understanding how certain proteins and receptors in the brain regulate neuronal signaling, particularly through G protein-coupled receptors (GPCRs). His research explores the interactions between different types of receptors and their accessory proteins, which play critical roles in brain function and can influence neurological and psychiatric disorders. By employing advanced techniques like microscopy and electrophysiology, the lab aims to elucidate the molecular mechanisms by which these receptors operate and their implications for treating various mental health conditions.