Dr. Matija Snuderl's lab at NYU School of Medicine focuses on understanding medulloblastoma, the most common malignant brain tumor in children. The team investigates how certain biological processes can be harnessed to induce maturation in these tumors, making them less aggressive and more treatable. Through advanced techniques in genetics and drug delivery, the lab aims to develop new therapies that are less toxic than current treatments.

Dr. Dan Littman's lab at NYU School of Medicine focuses on how the gut microbiome influences the effectiveness of immunotherapy in lung cancer. By studying specific bacterial species and their products, the lab aims to uncover mechanisms that enhance immune responses against tumors, potentially leading to better treatment outcomes for patients. This research could help identify which patients may benefit most from immunotherapy and reduce harmful side effects.

Dr. Jesús Torres-Vázquez's lab investigates the mechanisms behind how blood vessels achieve their proper size and structure, which is crucial for maintaining effective blood circulation. Using zebrafish as a primary model organism, the lab studies the signaling pathways and cellular processes that influence blood vessel caliber, including the roles of specific proteins and the effects of blood flow. Research in this lab aims to improve our understanding of cardiovascular health and the effects of vascular abnormalities.

Dr. Jessica E. Treisman's lab focuses on understanding the development and function of the corneal lens in the fruit fly Drosophila. By studying how specific cells in the retina differentiate and form the cornea, the lab aims to uncover mechanisms that could be relevant to human vision disorders like myopia and keratoconus. Their research combines genetic techniques and advanced imaging to explore cellular and molecular processes, providing insights that may help develop treatments for corneal diseases.

Dr. Jun Wang's lab at New York University focuses on understanding the mechanisms by which certain proteins in the tumor microenvironment suppress the immune system's ability to fight cancer. They are particularly interested in the roles of Siglec-15 and FGL1, two proteins that can inhibit T cell responses and promote tumor growth. By studying these proteins, the lab aims to develop new immunotherapies that can improve treatment outcomes for cancer patients who do not respond well to existing therapies.

Dr. Holger Knaut's lab at NYU School of Medicine focuses on understanding how skin repairs itself after injuries and how neuronal tissues migrate and split during development. They use zebrafish embryos for their research because these embryos are transparent, allowing for high-resolution imaging. By studying the molecular mechanisms behind wound healing and nerve formation, the lab aims to provide insights into potential treatments for skin disorders and neurological diseases.