Dr. Anil V Parwani's lab at Ohio State University focuses on cancer research through the collection and management of human biospecimens. They work as part of a cooperative network that provides high-quality biological samples to researchers, enabling groundbreaking studies in cancer treatment and personalized medicine. Their work supports a better understanding of cancer biology and helps develop new therapies based on human tissues and clinical data.

Dr. Thippeswamy's lab focuses on developing new treatments to help people recover from nerve agent poisoning, which can cause severe, long-lasting neurotoxic effects. The research aims to explore the effectiveness of two novel drugs in preventing and reversing brain damage and cognitive impairments caused by exposure to chemical warfare nerve agents. By testing these therapies in animal models, the lab aims to improve medical countermeasures for victims exposed to these harmful agents.

Dr. Kai Xu's lab at Ohio State University focuses on understanding henipaviruses, which can be deadly and have potential for future pandemics. The research aims to study the surface proteins of these viruses to develop better vaccines and treatments. This work is vital as henipaviruses can transfer between animals and humans, leading to serious outbreaks.

Dr. Jian Zhu's lab at Ohio State University focuses on understanding how HIV persists in the body, particularly in the brain, and how factors like drug use influence this persistence. They explore the role of host genes and epigenetic regulation in keeping HIV dormant and investigate potential therapies by repurposing existing FDA-approved drugs. By studying how drugs like cocaine affect gene expression related to HIV, the lab aims to develop strategies for effective treatments.

Dr. Jianrong Li's research lab focuses on developing innovative vaccines for gastrointestinal and respiratory viruses. One major project aims to create mucosal vaccines for norovirus, targeting a global health issue where no effective vaccines currently exist. Another project investigates RNA modifications in SARS-CoV-2, which could lead to improved treatments and vaccines against COVID-19. The lab combines advanced viral vector technology with cutting-edge genetic research to address critical public health challenges.

Dr. Xuefeng Liu's lab focuses on understanding prostate and bladder cancer, particularly the differences between African-American and European-American men. They develop innovative human cell models to study cancer progression and create non-invasive methods for monitoring bladder cancer. Their research aims to improve cancer detection and treatment outcomes by exploring the biological basis of cancer disparities and enhancing cancer cell culture techniques.

Dr. Christine A Petersen's research lab at Ohio State University focuses on understanding how skin immune responses influence the transmission of Leishmania, a parasite that causes serious illness in both dogs and humans. By studying the interactions between the parasite, sand flies that spread the infection, and the immune system in the skin, her work aims to develop better strategies for controlling Visceral Leishmaniasis, a disease that poses significant health risks. The lab explores innovative therapeutic approaches to modify immune responses and curb the disease's spread.

Dr. Megan Meuti's lab focuses on understanding the seasonal patterns of West Nile virus transmission, particularly how urban and rural environments affect the spread of the virus. By combining field data from mosquitoes and birds with advanced mathematical modeling, the lab aims to uncover the factors that drive WNV outbreaks each year. This research not only helps predict when and where outbreaks may occur but also informs public health interventions to protect both human and animal populations.