Dr. Md. Shenuarin Bhuiyan's lab at Louisiana State University focuses on understanding how a specific protein, Sigma 1 receptor, helps protect the heart under stress by regulating cell cleaning processes called macro-autophagy and mitophagy. The lab investigates the role of this receptor in heart failure to uncover new ways to treat the condition. Using genetically modified mice and advanced biochemical techniques, the lab aims to provide insights into the mechanisms that could lead to new therapies for heart diseases.

Dr. Oren Rom's lab focuses on understanding the role of macrophages in cardiovascular diseases, particularly how their metabolism affects plaque stability in atherosclerosis. The research aims to uncover mechanisms behind macrophage behavior, specifically their ability to clear dead cells (efferocytosis) in arterial plaques. By restoring certain metabolic pathways, the lab hopes to find new therapeutic strategies to prevent harmful plaque ruptures and improve cardiovascular health.

Dr. Anthony Wayne Orr's lab at Louisiana State University Health Sciences Center in Shreveport focuses on understanding and treating atherosclerosis, a major cause of cardiovascular disease. The lab investigates how cells interact with the extracellular matrix and how specific proteins influence inflammation and plaque stability. By exploring novel therapeutic strategies, the lab aims to develop targeted treatments that can both reduce dangerous inflammation and stabilize plaque in patients with cardiovascular disease.