Dr. Xintong Dong's lab at the University of Texas Dallas focuses on understanding how the body defends against urinary tract infections (UTIs) caused by bacteria. The lab works on a type of immune molecule called defensins to see how they protect the urinary tract and potentially cause discomfort. By using advanced genetic techniques and mouse models, the lab aims to develop new therapies to improve outcomes for patients suffering from UTIs and the pain they may cause.

Yannick Fotio's lab at the University of Texas Dallas focuses on understanding the biological mechanisms behind chronic pain, a significant health issue affecting millions. The research investigates the role of a specific enzyme, N-Acylethanolamine Acid Amidase (NAAA), in pain signaling and how it may contribute to the transition from acute to chronic pain. By exploring metabolic changes in cells after injury, the lab aims to uncover novel therapeutic targets for managing chronic pain.