Dr. Minglei Guo's lab studies how HIV and cocaine affect brain cells, particularly focusing on a type of brain cell called microglia. They are investigating how disruptions in lipid metabolism may lead to neurological problems in people living with HIV, especially those who also use cocaine. Through their research, they aim to find new ways to improve the quality of life for these individuals by targeting the underlying mechanisms of their neurological symptoms.

Dr. Yan Sanders' lab focuses on understanding and addressing the effects of cellular aging in the lungs of patients with Cystic Fibrosis (CF). They explore how epigenetic factors contribute to lung cell senescence, which leads to inflammation and decreased lung function. The research aims to develop new therapeutic strategies by targeting specific proteins that influence gene expression in aged lung cells, ultimately improving treatment for CF patients.