Wesley R. Legant's lab at the University of North Carolina Chapel Hill focuses on developing advanced microscopy techniques to study biological systems at multiple scales. By combining optical innovations and computer vision, the lab aims to create intelligent microscopes that can analyze live samples in real time. Their research investigates how proteins operate within the cell nucleus, enhancing our understanding of fundamental cellular processes.

Dr. Soumya Benhabbour's lab focuses on innovative drug delivery systems aimed at improving treatments for HIV and brain cancer. The lab develops long-acting injectable formulations and smart biomaterials that can enhance safety and efficacy, providing patients with better health outcomes and reducing the need for invasive procedures. They use advanced techniques such as ultrasound to improve cell therapy delivery and create novel systems that combine contraception with HIV prevention.

Dr. Li Wang's lab at UNC Chapel Hill focuses on developing advanced computational tools for analyzing brain imaging data, specifically to study early brain development in infants at risk of autism. The lab's goal is to create methods that can accurately segment and identify brain structures from MRI scans, potentially leading to earlier diagnosis and intervention for autism. By leveraging large-scale neuroimaging datasets, their research seeks to improve our understanding of autism development and create resources for the scientific community.

Dr. Weili Lin's lab focuses on understanding how various environmental factors, particularly during prenatal and early childhood periods, affect child development. This work is part of a large scale study involving thousands of mothers and infants, aiming to track developmental changes while assessing the effects of substances such as opioids and alcohol. The findings from this research will help shape public health policies to support child health across the U.S.

Dr. Jason R. Franz's lab focuses on understanding how age-related changes in the foot and ankle affect mobility in older adults. Their research aims to uncover the complex interactions between foot mechanics and muscle performance during walking, and how these can be enhanced through innovative shoe designs. Ultimately, the lab seeks to develop practical solutions to improve walking performance and reduce energy costs for the aging population, promoting independence and quality of life.

Dr. Louise Henderson's lab focuses on improving the health and monitoring of lung cancer survivors through innovative imaging techniques and data analysis. The research aims to reduce the risks of cancer recurrence and identify better strategies for lung cancer screening, especially for diverse populations. Using advanced deep learning methods and analysis of routine chest CT scans, the lab develops personalized surveillance strategies that tailor follow-up care to individual patient risks.

Dr. Brian O Diekman's lab studies the effects of DNA damage and cellular aging on osteoarthritis, a common joint disease. They focus on understanding how these factors lead to cell senescence, inflammation, and joint degeneration to develop better treatments. The lab uses advanced techniques to assess the extent of DNA damage and its effects on joint cells, aiming to spark new strategies to prevent and treat osteoarthritis.

Dr. Virginie Papadopoulou's lab focuses on developing innovative ultrasound-based therapies to enhance the treatment of chronic wounds, particularly those infected by tough-to-treat bacterial biofilms. By using advanced materials and techniques like phase-change contrast agents and therapeutic ultrasound, they aim to improve antibiotic delivery and effectiveness, reducing infection rates and promoting faster healing. This research has significant implications for public health, especially for individuals with conditions like diabetes that complicate wound healing.

Dr. Gianmarco Pinton's lab at the University of North Carolina Chapel Hill focuses on developing innovative ultrasound technologies for brain imaging and therapy. By using volumetric ultrasound, the lab aims to enable real-time monitoring and targeted neuromodulation of brain circuits in awake animals. This research has the potential to improve the understanding of brain function and lead to advanced treatments for neurological disorders.

Professor Zibo Li's lab focuses on developing new techniques for labeling biomolecules with fluorine-18, a radioactive isotope used in medical imaging. The research aims to create efficient tools for producing radiolabeled agents that can improve the visualization of drug distribution in the brain and enhance medical imaging technologies. This work could significantly impact the fields of drug discovery and cancer imaging.

Dr. Paul Dayton's lab focuses on developing advanced ultrasound imaging technologies that can provide high-resolution images of blood vessels, particularly in relation to cancer detection. The lab has created unique devices that allow for improved visualization of microvascular structures, which are crucial for identifying cancerous tissues. Their innovative approach aims to make these imaging techniques applicable to clinical settings, providing better tools for early cancer diagnosis.

Dr. Caterina Gallippi's lab at the University of North Carolina Chapel Hill focuses on developing advanced ultrasound technologies to improve the diagnosis and monitoring of serious health conditions. Their research aims to enhance breast cancer detection through a novel ultrasound method that assesses collagen organization in breast tissue and to monitor kidney transplant rejection without invasive procedures. By combining innovative imaging techniques with biomedical engineering, her lab addresses critical gaps in patient care and disease management.

Pew-Thian Yap's research lab focuses on understanding early brain development and improving MRI technology. They work on analyzing MRI data from infants to chart brain growth and investigate how structural changes relate to cognitive skills like language and motor function. Additionally, the lab is developing advanced imaging techniques to make MRI faster and more accurate, which could enhance diagnoses and treatment monitoring in clinical settings.