Dr. Daniel Abebayehu's lab at the University of Virginia focuses on understanding how inflammatory fibroblasts influence the wound healing process. By investigating the interactions between immune and stromal cells, the lab aims to pinpoint why some wounds heal properly while others lead to fibrosis, a condition that contributes to a significant number of deaths in the developed world. Through advanced techniques and models, the lab seeks to uncover new therapeutic targets to improve wound healing outcomes and address fibrotic disorders.

Evan Alexander Scott's lab at the University of Virginia focuses on developing innovative nanotherapeutic strategies to tackle chronic Chagas disease, particularly its associated heart condition, chronic Chagas cardiomyopathy (CCC). The lab aims to create treatments that not only reduce inflammation and cardiac damage but also target the parasite's reservoirs within the body. By optimizing drug delivery systems and minimizing toxicity, the lab seeks to provide effective therapies for patients battling this neglected tropical disease.

Dr. Rachelle L Crescenzi's research lab at the University of Virginia focuses on using advanced MRI techniques to better understand and diagnose lymphatic diseases, particularly lymphedema and lipedema. By developing a method called Sodium Adipose and Lymphatics Translational (SALT) MRI, the lab seeks to visualize how sodium accumulates in these conditions and aims to enhance clinical imaging to guide treatment. Their work not only aims to improve diagnostic strategies but also strives to pave the way for new therapeutic approaches in managing lymphatic disorders.

Dr. Sepideh Dolatshahi's lab at the University of Virginia focuses on understanding how antibodies are transferred from mothers to their infants through the placenta. By exploring the roles of different receptors involved in this process, the lab aims to optimize maternal vaccination strategies to provide better early-life immunity for newborns. Their work combines experimental biology with mathematical modeling to create more effective vaccines for expectant mothers.

Dr. Frederick H. Epstein's lab at the University of Virginia focuses on improving heart health through advanced imaging techniques. The lab studies epicardial adipose tissue, which is the fat surrounding the heart, and its impact on conditions like heart failure and coronary microvascular disease. By developing innovative methods to visualize this tissue, researchers aim to uncover new insights into cardiovascular diseases and potential therapeutic approaches.

Dr. Kevin A. Janes' research lab at the University of Virginia focuses on understanding viral infections and their impact on human health, specifically through innovative computational models and genetic analyses. They also explore the origins and progression of basal-like breast cancer, which is known for its aggressive nature and poor prognosis. By combining advanced modeling techniques with genetically engineered mouse models, the lab aims to uncover critical insights into both viral and cancer biology.

Dr. Jaime Mata's lab at the University of Virginia focuses on improving the diagnosis and management of acute cellular rejection in lung transplantation using innovative Hyperpolarized Gas MRI technology. This research aims to enhance the early detection of rejection, allowing for timely interventions and better outcomes for lung transplant patients. The lab integrates advanced imaging techniques with genomic profiling to create a comprehensive understanding of the immune responses involved in lung allograft health.

Dr. Craig H. Meyer's lab at the University of Virginia focuses on developing innovative magnetic resonance imaging (MRI) techniques for assessing lung health. By utilizing a novel 0.55 Tesla MRI scanner, the lab aims to create more effective imaging methods that can visualize both lung structure and function concurrently, which is particularly important for diagnosing chronic lung diseases without exposing patients to harmful radiation. Their work not only seeks to enhance MRI technology but also strives to make advanced lung imaging more accessible, especially for vulnerable populations like children and pregnant women.

Dr. Jiang He's lab at the University of Virginia focuses on developing new imaging and treatment methods for mesothelioma, a challenging form of cancer. The lab is working on a human monoclonal antibody that targets a specific tumor marker found in various mesothelioma subtypes. By using advanced imaging techniques, such as SPECT, and targeted alpha therapy, they aim to improve treatment outcomes for patients, especially for those suffering from difficult-to-treat forms of the disease.

Richard J. Price's research lab at the University of Virginia focuses on innovative therapies for neurological diseases like Alzheimer's disease and cerebral cavernous malformations (CCMs). The lab uses advanced techniques such as magnetic resonance imaging (MRI) and focused ultrasound (FUS) to enhance drug delivery and manipulate microglial responses in the brain. Their ultimate goal is to improve cognitive function and minimize the impact of these diseases through targeted, non-invasive treatments.

The lab focuses on developing new biomaterial scaffolds designed to enhance the healing process of diabetic wounds. By engineering a special type of hydrogel called Microporous Annealed Particle gel (MAP gel), the team aims to reduce inflammation, improve tissue integration, and support better blood vessel formation in wounds. With a combination of in vitro and in vivo experiments, they work to systematically improve these hydrogels for effective treatment alternatives for diabetic patients.