Amy Fowler · Biomedical Engineering
Dr. Amy Fowler's lab at the University of Wisconsin-Madison focuses on improving how breast cancer patients are treated by developing advanced imaging techniques to help predict how well they will respond to a specific type of hormone therapy. The research aims to create more personalized treatment plans by using non-invasive imaging methods that can detect changes in tumors after treatment begins. This innovative approach is expected to lead to better outcomes for patients with hormone receptor positive breast cancer.
Andrew L Wentland · Biomedical Engineering
Dr. Andrew L. Wentland's lab focuses on improving CT urography, a technique used to diagnose causes of blood in urine. They have developed a novel synthetic imaging method that enhances the accuracy of kidney imaging while significantly reducing the radiation dose and the time required for the examination. The lab combines advanced image processing with deep learning to create images that help in diagnosing kidney conditions more safely and efficiently.
Pallavi Tiwari · Biomedical Engineering
Dr. Pallavi Tiwari's lab at the University of Wisconsin-Madison focuses on advancing non-invasive imaging techniques to better understand glioblastoma, a challenging brain cancer. The lab is developing innovative radiomic spatial maps to accurately identify the extent of viable tumors in MRI scans, helping clinicians differentiate between tumor infiltration and normal brain edema. This research aims to improve treatment planning and outcomes for patients with glioblastoma by reducing the need for invasive biopsies.
Deric L Wheeler · Biomedical Engineering
Dr. Deric Wheeler's lab focuses on improving treatments for head and neck cancer (HNC) by exploring how certain proteins contribute to resistance against targeted therapies, specifically the drug cetuximab. By studying both human tumor samples and patient-derived models, the lab aims to understand the molecular mechanisms of resistance and to identify ways to overcome it using combinations of therapies. Their ultimate goal is to enhance treatment outcomes and refine existing therapeutic approaches for HNC patients.
Randall J. Kimple · Biomedical Engineering
Dr. Kimple's lab focuses on improving models used to study head and neck cancer by examining how different methods of implanting patient tumors in mice affect the accuracy and relevance of research findings. This work helps ensure that treatments tested in these models are more predictive of their effects in actual patients. By exploring the interactions between tumors and the immune system, the lab aims to enhance the development of novel therapies for head and neck cancer patients.
Ali Pirasteh · Biomedical Engineering
Dr. Ali Pirasteh's lab focuses on improving the diagnosis and treatment of chronic liver diseases, which affect a large portion of the global population. The primary research involves developing a new non-invasive imaging technique using positron emission tomography (PET) to detect liver fibrogenesis, the process that leads to liver scarring and various complications including liver failure. By targeting activated liver cells, this method aims to provide critical information about liver health and treatment efficacy over traditional biopsy methods, enhancing care for millions who suffer from chronic liver conditions.
Alan Blair Mcmillan · Biomedical Engineering
Dr. Alan Blair McMillan's lab at the University of Wisconsin-Madison focuses on understanding how chronic epilepsy affects brain aging and cognitive health in older adults. By using advanced neuroimaging techniques, the lab aims to identify specific biomarkers that indicate accelerated brain aging in individuals with this condition. The research could reveal risk and resilience factors that influence cognitive outcomes, ultimately providing insights into potential protective strategies for aging patients with epilepsy.
Veena A Nair · Biomedical Engineering
Dr. Veena A. Nair's lab focuses on understanding the brain changes that occur after a stroke and how these changes can lead to cognitive impairments and dementia. The lab conducts research using advanced MRI techniques and machine learning to identify and model the complex interactions between various risk factors, including socioeconomic status and brain health, following a stroke. By studying underrepresented communities, the lab aims to improve diagnosis and treatment strategies for stroke survivors at risk of developing cognitive deficits.
Shaoqin - Gong · Biomedical Engineering
Dr. Shaoqin Gong's lab at the University of Wisconsin-Madison focuses on developing new treatments for Alzheimer's disease using advanced genetic engineering techniques. They aim to create non-viral nanovectors that can effectively deliver CRISPR genome editing tools across the blood-brain barrier, which is crucial for treating neurodegenerative diseases that affect large areas of the brain. The lab's innovative approach seeks to improve safety and efficiency in gene delivery, potentially leading to new therapeutic options for Alzheimer's patients.
Christopher L Brace · Biomedical Engineering
Dr. Christopher Brace's lab at the University of Wisconsin-Madison focuses on innovative treatments for pediatric limb length discrepancies. The lab is developing a non-invasive method using microwave energy to disrupt growth plates, offering a safer, quicker recovery compared to traditional surgical methods. Their research aims to improve the quality of life for children who suffer from these conditions by reducing recovery time and medical complications.
Lonie Salkowski · Biomedical Engineering
Lonie Salkowski's lab at the University of Wisconsin-Madison focuses on improving cancer detection through enhanced training for radiology residents in screening mammography. The lab is developing a specialized simulation system to help residents practice their interpretive skills in a safe environment, aiming to reduce errors in diagnosing breast cancer. Their research combines radiology, computer science, and educational psychology to foster better outcomes for women's health.