Rebecca Scheck · Chemistry
The Scheck lab at Tufts University focuses on understanding how chemical modifications of proteins, specifically glycation and ubiquitination, impact cellular functions and contribute to diseases like cancer and diabetes. By developing innovative tools to study these modifications in living cells, the lab aims to uncover new therapeutic targets for addressing age-related disorders and other health issues. Their research combines advanced chemical biology techniques with a deep understanding of cellular signaling networks.
Joshua A Kritzer · Chemistry
The Kritzer lab at Tufts University focuses on developing new therapeutic methods to combat late-stage cancers. Their research revolves around inhibiting autophagy, a process that degrades proteins within cells, which can be detrimental when cancers use it to survive. They are creating novel inhibitors and chimeras to selectively target and degrade key proteins involved in this process. Additionally, the lab is working to improve how large-molecule drugs penetrate cells to enhance their effectiveness.
Charles R Mace · Chemistry
Dr. Charles R Mace's lab at Tufts University focuses on developing innovative tools for collecting and processing blood samples, especially for patients who need regular health monitoring without the hassle of hospital visits. Their work is aimed at enhancing healthcare access by creating user-friendly devices that allow for safe self-collection of blood samples at home, which can then be easily mailed to labs. This research not only seeks to improve patient experience but also aims to support advancements in telemedicine and healthcare equity.