Roy Wollman · Chemistry
Dr. Roy Wollman's lab at UCLA focuses on innovating methods to study the anatomy and function of organs using advanced imaging techniques. The lab is developing a groundbreaking approach called dredFISH, which allows researchers to map the gene expression of entire organs in 3D, moving beyond traditional 2D techniques. By creating detailed atlases of cell types and gene expression, this research has the potential to transform our understanding of biological structures and their functions.
Juli Feigon · Chemistry
Dr. Juli Feigon's lab at UCLA studies the structure and function of telomerase, the enzyme responsible for maintaining telomeres, which are the protective ends of chromosomes. By combining advanced techniques like cryo-electron microscopy and NMR spectroscopy, the lab aims to understand how telomerase works, how it is regulated, and how mutations can lead to diseases like dyskeratosis congenita and aplastic anemia. This research is significant for revealing insights into aging, stem cell function, and potential therapeutic targets for various diseases.
Neil K. Garg · Chemistry
Dr. Neil K. Garg's research lab at UCLA focuses on developing innovative chemical synthesis methods using unusual building blocks to create complex molecular structures. The work aims to improve how we construct small molecules that are important for natural products and medicines. By exploring strained intermediates with distorted geometries, the lab seeks to uncover new strategies for synthesizing drugs with intricate designs.