Dr. Marcos M. Pires' lab at the University of Virginia focuses on understanding how bacteria like Mycobacterium tuberculosis and Acinetobacter baumannii resist antibiotics. By investigating the structural properties of bacterial membranes, the lab aims to uncover ways to enhance the effectiveness of existing antibiotics and develop new ones. They utilize advanced screening methods to analyze how drugs interact with bacterial cells, which is critical for improving treatment options for drug-resistant infections.

B. Jill Venton's research lab at the University of Virginia focuses on developing innovative tools for pharmacogenomic screening and understanding neuromodulation in the brain. One key project aims to create a low-cost, portable microfluidic system that can quickly analyze genetic factors influencing how patients metabolize antidepressants. Another project investigates the role of adenosine in modulating brain activity, utilizing advanced techniques to measure various neurotransmitters simultaneously. This work has the potential to improve treatment for conditions like major depression and brain injuries.