Dr. Donald O Freytes' lab at NC State University focuses on developing a new, non-invasive treatment for voice disorders that affect millions of Americans. The lab studies a special extract from vocal folds, which has shown promise in healing injuries and reducing scarring without needing surgery. Their work includes testing how this extract works at a molecular level and evaluating its safety and effectiveness in animal models.

Dr. Alon Greenbaum's lab at North Carolina State University focuses on developing advanced imaging techniques to study brain cells, particularly glial cells, which are important for brain health and function. Their innovative platform allows for fast and detailed analysis of entire brain tissues, helping to understand how changes in glial cell development relate to diseases like Alzheimer's and multiple sclerosis. By optimizing imaging and machine learning, the lab aims to uncover the mechanisms behind brain cell production and their potential role in regenerative medicine.

Dr. He Huang's research lab focuses on enhancing the functionality and accessibility of powered prosthetic devices for individuals with lower limb amputations. By utilizing advanced techniques like reinforcement learning and neural interfacing, the lab aims to personalize prosthetic control, improve balance, and ultimately enhance the quality of life for amputees. Their work addresses critical challenges such as gait efficiency and postural stability in daily activities.

Dr. Matthew B. Fisher's lab at North Carolina State University focuses on understanding knee injuries, particularly those involving the anterior cruciate ligament (ACL) and meniscus. They explore how hormones and growth affect knee joint function and the impacts of surgical techniques on recovery and joint health. Using advanced materials science, they also aim to develop better scaffolds for tissue engineering that mimic the structure and function of knee tissues to enhance healing and prevent further injuries.

Nathan C. Crook's research lab focuses on developing novel therapies to combat Clostridioides difficile infection (CDI), a severe gastrointestinal illness. By engineering probiotic yeast to deliver specially designed peptides that neutralize the toxins produced by C. difficile, the lab aims to create a new treatment approach that is more effective and fewer side effects than traditional antibiotics. The research integrates techniques from molecular biology, microbiology, and bioengineering to create innovative solutions to this public health challenge.

Dr. Marie Muller's lab focuses on developing advanced ultrasound techniques for assessing lung diseases and cancer. The lab aims to create non-invasive methods for real-time monitoring and diagnosis, improving accuracy and patient care without exposing them to harmful radiation. By quantifying lung conditions and angiogenesis, the lab seeks to enhance cardiovascular and cancer treatment outcomes.

Dr. Xiaoning Jiang's lab focuses on developing advanced ultrasound technologies to improve treatments for deep vein thrombosis (DVT), a condition that affects millions of Americans. The lab is working on a new catheter system that combines ultrasound imaging and therapy to rapidly dissolve blood clots while minimizing risks of bleeding and vessel damage. Their approach seeks to enhance the effectiveness and safety of existing treatments to ultimately save lives and improve outcomes for patients with DVT.

Dr. David Zaharoff's lab at North Carolina State University focuses on developing immunotherapies for bladder cancer that not only aid canine patients but may also benefit human treatments. Their work emphasizes the use of interleukin-12 delivered through a biopolymer to trigger immune responses against invasive bladder tumors in dogs with spontaneous cancer. The research aims to establish safety and effectiveness levels of this therapy in dogs, paving the way for potential human clinical trials in the future.