Dr. Kailash Gulshan's lab focuses on understanding how inflammation related to lipid metabolism contributes to diseases like atherosclerosis and progressive familial intrahepatic cholestasis (PFIC1). The lab investigates the role of specific proteins and metabolic pathways in regulating inflammation and aims to develop new therapeutic strategies for these conditions. By employing advanced techniques, the lab seeks to uncover novel mechanisms that could lead to effective treatments.

Dr. Mahesh Ramamoorthy's lab at Cleveland State University focuses on understanding how specific proteins influence blood cell development, especially in the production of hemoglobin. They study a protein called Stag1, which plays a crucial role in the maturation of red blood cells. By uncovering the mechanisms of how Stag1 regulates gene expression during this process, the lab aims to provide insights that could lead to new treatments for blood disorders like anemia and thalassemia.