Dr. Christin Burd's lab at Ohio State University studies how specific mutations in the NRAS gene lead to various types of cancer, focusing primarily on melanoma and other malignancies. The lab examines the unique biochemical behaviors of different NRAS mutant proteins, seeking to understand how these differences affect tumor growth and response to treatments. By leveraging a combination of structural biology and experimental approaches, the lab aims to identify potential new therapeutic targets for RAS-driven cancers.

Dr. Sharon Amacher's lab at Ohio State University focuses on understanding how rhythmic patterns of gene expression, known as biological oscillators, regulate important developmental processes. Their research explores these oscillators' roles in processes like organ development and cellular differentiation, especially during the formation of somites, which are essential for building vertebrate body structures. By studying various model organisms, they aim to uncover the genetic and molecular mechanisms behind these oscillatory patterns, contributing to our knowledge of developmental biology and stem cell regulation.