Dr. Jlenia Guarnerio's lab focuses on improving treatments for soft-tissue sarcomas, a type of cancer with low survival rates. The research investigates how circular RNAs can affect the immune response to a specific cancer drug called Abemaciclib. By understanding these interactions, the lab aims to enhance the drug's effectiveness and improve outcomes for patients.

Dr. Sadhan Majumder's lab focuses on understanding chronic neuropathic pain and how to improve opioid treatment safety. They investigate the role of a protein called REST in regulating opioid receptors in nerve cells, which can affect how the body responds to pain. The research aims to develop new strategies to enhance pain relief while minimizing the risk of addiction and tolerance to opioids.

Dr. Georgios Karras's lab focuses on understanding how certain chemicals, known as aldehydes, can damage our DNA and proteins, leading to diseases like cancer. They investigate how these harmful substances disrupt essential protein functions and contribute to genetic instability. By uncovering these mechanisms, the lab aims to develop new strategies for managing diseases linked to aging and lifestyle choices, potentially leading to better diagnostic and treatment approaches.