Dr. Charles Hoeffer's lab at the University of Colorado is focused on understanding how genetic factors in Down syndrome (DS) contribute to sleep problems and their relationship with Alzheimer’s disease (AD). They investigate specific genes that may disrupt sleep and worsen cognitive impairments, aiming to uncover the mechanisms behind these issues to improve quality of life for individuals with DS. Overall, this research seeks to bridge gaps in knowledge about sleep disturbances and neurodegeneration in DS-related Alzheimer’s disease.

Dr. Andrew David Grotzinger's lab at the University of Colorado focuses on understanding the genetic underpinnings of Major Depressive Disorder (MDD). Utilizing advanced genomic techniques, the lab aims to identify distinct genetic subtypes of MDD and their associations with various biological pathways. Their research has the potential to improve diagnosis and treatment options for individuals suffering from depression, offering insights tailored to different patient profiles.

Daniel Gustavson's lab at the University of Colorado focuses on understanding how music engagement can protect against substance use in adolescents. The research explores whether connecting with music influences behaviors related to substance use and how genetic and environmental factors interact with this relationship. By analyzing extensive longitudinal data, the lab aims to identify intervention strategies that could help at-risk youth before they develop substance use disorders.