Lynn Jorde's lab focuses on understanding human genetic variation and its links to diseases. They study how mutations occur across generations in families from Utah, investigating the relationship between genetic changes, aging, and health outcomes like lifespan and menopause age. The lab also works on developing new methods to analyze genetic data, particularly using whole-genome sequencing and RNA sequencing.

Dr. Gabor T Marth's lab focuses on improving how we detect somatic mutations, which are changes in our DNA that can lead to diseases like cancer. One key project is developing a software called RUFUS to enhance the sensitivity and accuracy of detecting these mutations across various types and frequencies. Another project, Calypso, aims to create a user-friendly web tool for clinical teams to collaborate on genomic diagnostics over time, particularly for complex cases like those in neonatal care and undiagnosed disease clinics.

Dr. Aaron R. Quinlan's lab focuses on creating innovative algorithms and tools to analyze large genomic datasets. As genomics research expands, existing methods struggle to keep up with the size and complexity of new data. The lab aims to enhance the capabilities of genome arithmetic, allowing researchers to effectively explore, compare, and visualize vast genomic information, thus facilitating new discoveries in the field.