Dr. Brian Wigdahl's lab at Drexel University focuses on developing advanced gene editing strategies to combat HIV-1 infection, particularly in the body's various tissue reservoirs, including the brain. By utilizing CRISPR technology, the lab aims to enhance the precision and effectiveness of treatments targeting the diverse strains of HIV found in patients. Their innovative research combines high-throughput biological assays and computational biology to improve gene editing outcomes, ultimately seeking to provide a potential cure for HIV.

Dr. Sandhya Kortagere's lab at Drexel University focuses on developing new therapies for epilepsy, a condition affecting millions worldwide. The lab aims to create a novel drug that can help patients who do not respond to current treatments. By studying how a specific glutamate transporter works in the brain, the lab is working to improve seizure control and promote long-term brain health.

Dr. Akhil B Vaidya's lab at Drexel University focuses on understanding fundamental aspects of malaria parasites, particularly how they maintain sodium and lipid balance, and the roles of mitochondria in their survival. The research aims to uncover how these processes can be disrupted by new drugs to combat malaria, a disease that causes significant global health issues. By investigating the molecular pathways involved, the lab strives to identify new targets for antimalarial drug development.

Dr. Hangjun Ke's research lab focuses on understanding the biology of malaria parasites, particularly during the ring stage of their lifecycle. This stage is crucial because it allows the parasite to evade the immune system and is less responsive to existing antimalarial drugs. By studying the unique ways these parasites generate energy without ATP, the lab aims to identify new strategies to combat malaria and improve treatment outcomes.

Dr. James Matthew Burns' lab focuses on developing innovative malaria vaccines using advanced mRNA technology. The research aims to create a multivalent vaccine that targets different stages of malaria parasites, potentially providing better protection against the disease. This involves understanding immune responses and optimizing vaccine formulations to enhance effectiveness.