David Emmet Nelson · Microbiology & Immunology
David Emmet Nelson's lab focuses on understanding chlamydia infections in men, particularly how certain men may resist the infection and transmit it less. The research aims to explore the relationship between the male immune system, the microbiome in the urethra, and the dynamics of chlamydia infections. This work could lead to better prevention strategies for chlamydia, especially among women.
Wei Luo · Microbiology & Immunology
Dr. Wei Luo's lab focuses on developing a universal influenza vaccine by understanding and overcoming immunodominance in B cell responses. They work on novel nanoparticle adjuvants that enhance immune response against less dominant, yet crucial parts of the influenza virus. The research aims to manipulate B cell maturation and antibody diversity to create more effective vaccines against influenza.
Martin Joseph Richer · Microbiology & Immunology
Dr. Martin Joseph Richer's lab at Indiana University Indianapolis focuses on understanding how diet, specifically high salt intake, affects immune responses to viral infections. Their research investigates whether excessive salt can hinder the function of critical immune cells, particularly CD8 T cells, which play a vital role in fighting off viruses. By exploring the mechanisms involved, they aim to uncover potential therapeutic targets to improve immune function in individuals consuming high levels of dietary salt.
Randy R Brutkiewicz · Microbiology & Immunology
Dr. Randy Brutkiewicz's lab at Indiana University Indianapolis focuses on understanding how the immune system, specifically a type of immune cell called MAIT cells, contributes to Alzheimer's disease (AD) and its associated neuroinflammation. By investigating the mechanisms by which these cells and their interactions with brain cells like microglia and astrocytes impact AD pathology, the lab aims to uncover new therapeutic targets for this devastating disease.